Epstein-Barr virus neutralizing and early antigen antibodies in multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Comparison of Epstein Barr virus antibodies and Tcell cytokines production in patients with multiple sclerosis and healthy individuals
Abstract Background: Multiple sclerosis (MS) is the most common autoimmune disease of central nervous system with destruction of myelin sheath mediated by auto reactive CD4+ T Lymphocytes. Because of the possible role of Epstein-Barr virus in etiology of MS and T cells immune response, the aim of this study was to evaluate anti-Epstein Barr virus antibodies as a marker of reactivity and p...
متن کاملMultiple sclerosis and Epstein-Barr virus.
CONTEXT Infection with Epstein-Barr virus (EBV) has been associated with an increased risk of multiple sclerosis (MS), but the temporal relationship remains unclear. OBJECTIVE To determine whether antibodies to EBV are elevated before the onset of MS. DESIGN, SETTING, AND POPULATION Nested case-control study conducted among more than 3 million US military personnel with blood samples collec...
متن کاملEpstein-Barr virus in pediatric multiple sclerosis.
CONTEXT Infection with common viruses, particularly Epstein-Barr virus (EBV), has been postulated to contribute to the pathobiology of multiple sclerosis (MS). Detailed virological studies in pediatric MS have not been previously reported. OBJECTIVE To evaluate whether children with MS are more likely to be seropositive for EBV or other common viruses than their healthy age-matched peers. D...
متن کاملEpstein-Barr virus and multiple sclerosis.
Epstein-Barr virus (EBV) is one of the most common and successful human viruses, infecting more than 90% of the world's adult population. Despite its strong tumorigenic potential, most virus carriers remain healthy due to maintenance of a delicate balance between the host's immune system, which limits production of virus particles, and the virus, which persists for the duration of the host's li...
متن کاملEpstein-Barr virus and disease activity in multiple sclerosis.
OBJECTIVES To study in relapsing-remitting (RR) multiple sclerosis (MS) whether exacerbations and brain activity as measured by magnetic resonance imaging (MRI) are associated with plasma levels of anti-Epstein Barr (EBV) antibodies and EBV DNA. METHODS This was a prospective study with 73 RR MS patients followed for an average of 1.7 years with frequent neurological examination and blood sam...
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ژورنال
عنوان ژورنال: European Journal of Neurology
سال: 2010
ISSN: 1351-5101
DOI: 10.1111/j.1468-1331.2010.03005.x